Category Archives: Science Research Technology

Science Research Technology

High-tech information systems take the place of a note stuck on a lamp

Success story in the „Incisions and insights“ workshop series – Reutlingen University and RZ Medizintechnik develop innovative tablet solution for the operating theatre

High-tech information systems take the place of a note stuck on a lamp

Incisions and insights workshop „heart, lungs, thorax“ (Source: Michael Latz/BioRegio STERN)

(Stuttgart/Tübingen/Reutlingen/Tuttlingen) – The Computer-Assisted Medicine research group at Reutlingen University’s School of Informatics is working with RZ Medizintechnik GmbH to develop a special tablet that provides surgeons with data and patient information directly in the operating theatre. The idea for the development resulted from „Incisions and insights“, a unique workshop series that brings together medtech engineers and surgeons around the operating table to identify and then kick-start the innovations that are needed. The project is now receiving funding from the Baden-Württemberg Ministry of Science, Research and the Arts and the European Regional Development Fund (ERDF). The first systems are due to be available in operating theatres in 2019.

The first invitations to „Incisions and insights“ were sent out in June 2016. This completely new workshop series is organised by BioRegio STERN Management GmbH in conjunction with Verein zur Förderung der Biotechnologie und Medizintechnik e. V. (Society for the Promotion of Biotechnology and Medical Technology) and the Inter-University Center for Medical Technologies Stuttgart-Tübingen (IZST). It offers medtech engineers an exclusive opportunity to join medical directors and consultants from a wide range of disciplines around the operating table and discuss medical needs. The combination of live streaming from the operating theatre and practical exercises in the operating theatre at the University of Tübingen’s Institute of Clinical Anatomy and Cell Analysis is unique. The open dialogue is intended to inspire the participants to come up with completely new ideas, instruments and methods for surgery.

„Small and medium-sized enterprises often don’t have the opportunity to talk directly to consultants,“ says Andreas Banescu, from Tuttlingen-based RZ Medizintechnik GmbH. He was therefore pleased to take up the invitation to the workshop, which focused on pelvic surgery, and was able to see for himself what problems surgeons have with lighting and visualisation in the operating theatre. Whether operating endoscopically or openly, surgeons would like to have monitors that do not force them to look away from the patient but are instead positioned within their field of vision.

Following in-depth discussion, it was the idea of a tablet for direct use at the operating table that won over Prof. Bernhard Hirt, Director of the Institute of Clinical Anatomy and Cell Analysis, and Prof. Arnulf Stenzl, Medical Director of the University Department of Urology and Director of the Inter-University Center for Medical Technologies Stuttgart-Tübingen (IZST). The developers from the medtech SME are now working with medtech informatics PhD students from Reutlingen University on a tablet that features ingenious applications. Prof. Oliver Burgert from the School of Informatics is responsible for the information system, which ensures surgeons can access all the information that is relevant to them during an operation without having to turn away from the operating area. „Despite all the technology available, it’s still very common to see a note stuck to a lamp in an operating theatre,“ explains Burgert. „Our software is designed so that surgeons can preselect what data, covering areas such as pre-existing conditions, intolerances and radiological images, is to be available to them and at what point during the operation. They can then easily view and use this information via a sterile-packed tablet near the patient. The system is intended not only to supply patient data but also to aid visualisation, for example during an endoscopy, and to document the entire surgical procedure where required.

The first prototypes have been successfully tested, with the first prototypical test in an operating theatre already planned for 2019. This has also been made possible by funding of 477,000 euros, with one half coming from the Baden-Württemberg Ministry of Science, Research and the Arts and the other 50 per cent from the European Regional Development Fund (ERDF). The tablet instantly won over the experts from the recently announced HAW-KMU-TT programme, which aims to encourage research-oriented technology transfer between universities of applied sciences and small and medium-sized enterprises (SMEs) in the region.

„Incisions and insights“ is a success story that is set to continue,“ insists BioRegio STERN’s Managing Director Dr. Klaus Eichenberg. „Two workshops are planned for next year – „Extremities and the musculoskeletal system“ on 6 February and „Intelligent permanent implants“ on 3 July. We look forward to many more stimulating discussions and exciting innovations.“

About BioRegio STERN Management GmbH:
BioRegio STERN Management GmbH promotes economic development in the life sciences industry, helping to strengthen the region as a business location by supporting innovations and start-up companies in the public interest. It is the main point of contact for company founders and entrepreneurs in the Stuttgart and Neckar-Alb regions, including the cities of Tübingen and Reutlingen.
The STERN BioRegion is one of the largest and most successful bioregions in Germany. Its unique selling points include a mix of biotech and medtech companies that is outstanding in Germany and regional clusters in the fields of automation technology and mechanical engineering.

Company-Contact
BioRegio STERN Management GmbH
Dr. Klaus Eichenberg
Friedrichstrasse 10
70174 Stuttgart
Phone: +49 (0)711-870354-0
E-Mail: info@bioregio-stern.de
Url: http://www.bioregio-stern.de/en

Press
Zeeb Kommunikation GmbH
Anja Pätzold
Hohenheimer Strasse 58a
70184 Stuttgart
Phone: +49 (0)711-6070719
E-Mail: info@zeeb.info
Url: http://www.zeeb-kommunikation.de

Science Research Technology

„Back in the Game“ app supporting treatment for depression wins at Demo Day 2018

Ideas presented by teams in 100-day MedTech Startup School 2018

"Back in the Game" app supporting treatment for depression wins at Demo Day 2018

MedTech Demo Day 2018 (Source: Armin Burkhardt)

(Stuttgart/Tübingen) – Teams of researchers, doctors and students pitched their medtech startup ideas to investors and industry experts at this year’s MedTech Demo Day. The „Back in the Game“ app impressed the most this year. Developed by a research team at the University Hospital of Tübingen, it is intended to help people suffering from depression. The Demo Day is organised by the MedTech Startup School and BioRegio STERN Management GmbH in cooperation with the Medical Innovations Foundation, the University Hospital of Tübingen and the University of Tübingen’s Technology Transfer Office.

The Demo Day was being held for the fourth time and saw a group of young researchers from Tübingen present „Back in the Game“ – an app that aims to help people with depression. The mobile phone game is a joint development by psychologists, neurobiologists, doctors and gaming specialists to assist patients while they are waiting for their treatment to start and also to prevent relapses. Professor Christian Plewnia, who heads the University Hospital of Tübingen’s Neurophysiology & Interventional Neuropsychiatry group, is supervising the team of developers.

The Demo Day took place on 15 October 2018 and provided a thrilling conclusion to a 100-day accelerator programme for selected teams pitching their laboratory/practice-based healthcare ideas to potential investors, business specialists and health experts. Prior to the event, the young researchers from a whole host of different sectors had worked on their business models with economists, scientists, doctors and lawyers – a process during which they gathered the necessary startup know-how. Amongst other things, they were required to prepare a business case and perform a market validation. At the Bootshaus am Neckar in Tübingen, they were then thrown into the lions‘ den, as it were, unveiling their proposal to an audience from the worlds of business and science. All the guests were then able to vote for their favourite, with the majority opting for „Back in the Game“.

As Dr. Klaus Eichenberg, Managing Director of BioRegio STERN Management GmbH, explains: „We’ve been supporting the MedTech Startup School from the outset because good life science ideas are reliant on professional backing if they are to become a successful startup. The fact that many of the projects from previous years have already made significant progress is testament to the quality of the programme.“

The MedTech Startup School, the Startup Booster and the Medical Innovations Explorer together form the Baden-Württemberg Life Science Accelerator. The school is supported by the Baden-Württemberg State Ministry of Economic Affairs, Labour and Housing, the German Federal Ministry of Science, Research and the Arts, and Baden-Württemberg’s state startup initiative with resources from the ESF.

About BioRegio STERN Management GmbH:
BioRegio STERN Management GmbH promotes economic development in the life sciences industry, helping to strengthen the region as a business location by supporting innovations and start-up companies in the public interest. It is the main point of contact for company founders and entrepreneurs in the Stuttgart and Neckar-Alb regions, including the cities of Tübingen and Reutlingen.
The STERN BioRegion is one of the largest and most successful bioregions in Germany. Its unique selling points include a mix of biotech and medtech companies that is outstanding in Germany and regional clusters in the fields of automation technology and mechanical engineering.

Company-Contact
BioRegio STERN Management GmbH
Dr. Klaus Eichenberg
Friedrichstrasse 10
70174 Stuttgart
Phone: +49 (0)711-870354-0
E-Mail: info@bioregio-stern.de
Url: http://www.bioregio-stern.de/en

Press
Zeeb Kommunikation GmbH
Anja Pätzold
Hohenheimer Strasse 58a
70184 Stuttgart
Phone: +49 (0)711-6070719
E-Mail: info@zeeb.info
Url: http://www.zeeb-kommunikation.de

Science Research Technology

Wingcopter developes parcel drone for DHL

Rapid response from the air: medicines successfully delivered using a parcel drone in East Africa

Wingcopter developes parcel drone for DHL

The autonomous DHL Parcelcopter 4.0 completed the 60 km flight from the mainland in 40 minutes.

Darmstadt/Eschborn/Bonn, 4 October 2018: Revolutionising the delivery of medicines to remote areas using drones – the pilot project Deliver Future proves that it“s not science fiction. Three experts in their respective fields are making it happen: The German drone manufacturer Wingcopter, the Deutsche Gesellschaft für Internationale Zusammenarbeit (GIZ) GmbH on behalf of the German Federal Ministry for Economic Cooperation and Development (BMZ) and DHL. Over a six-month period, they successfully tested the delivery of medicines using a drone to an island in Lake Victoria. During the trials, the autonomous DHL Parcelcopter 4.0 completed the 60 km flight from the mainland to the island in 40 minutes on average. A total of 2,200 km were flown and roughly 2,000 flight minutes recorded during the pilot project. The drone thus opens up new opportunities to adress the logistic challenges in the public health sector in many parts of Africa, especially supplying hospitals and pharmacies. Medical care for the roughly 400,000 residents of the Ukerewe island district of Lake Victoria, for instance, is severely limited. This is partly due to the poor infrastructure and difficult terrain. Six hours are needed to cover the overland route of 240 km. That makes it nearly impossible to provide emergency medication or to quickly refill cool chain commodities that are out of stock. A key feature is that the DHL Parcelcopter 4.0 barely needs any infrastructure as it takes off and lands vertically. After delivering its cargo, it can easily be loaded with blood and laboratory samples to take back to the mainland. In future, the Parcelcopter could therefore not only improve logistics in the public health sector: it has the potential to help prevent crises worldwide, for example allowing an early response to slow the spread of viral diseases like Ebola.
Short film about the Deliver Future pilot project. Find press photos and logo files here.

Wingcopter is an award-winning German manufacturer of innovative drones for logistics, surveying, monitoring and inspection. In order to achieve a new dimension of efficiency and close the market gap between commercial drones, helicopters and fixed wing aircraft, the startup has specially developed and patented a unique tilting rotor mechanism. This combines the advantages of two drone types in one: The electrically powered Wingcopter drones can take off and land vertically like multicopters in a minimum of space. For efficient forward flight, the rotors can be tilted and the drone transforms into an unmanned fixed-wing aircraft in seconds. This enables long ranges of up to 100 km and a Guinness World Record top speed of 240 km/h. The Wingcopter flies autonomously and reliably even in strong winds or heavy rain. In addition to the transport boxes filled with goods or medical commodities, a variety of sensors such as full format cameras or precise laser measuring devices can easily be attached. These sensors are utilized in applications like infrastructure monitoring of pipelines, power lines or railway lines, for search and rescue missions or disaster control, as well as for mapping of huge landscapes and optimizing precision agriculture and geological research. Already today, Wingcopter is shaping the future of aviation and is dedicated to improving the lives of people worldwide by enabling meaningful civil applications.

Contact
Wingcopter Holding GmbH & Co. KG
Tom Plümmer
Kleyerstraße 7
64295 Darmstadt
Phone: +49 175 26 26 272
E-Mail: info@wingcopter.com
Url: http://www.wingcopter.com

Science Research Technology

35 years of Palas GmbH:

Pioneer and global market leader with profound expertise of nanoparticles

35 years of Palas GmbH:

Test bench presentation in Utrecht 1985 (Source: Palas GmbH)

When Leander Moelter founded Palas GmbH in 1983, aerosol technology was still in its infancy in Germany. And yet he had the vision of developing a profitable business based on „measuring and generating particles“. 35 years later, Palas® holds not only 74 patent applications but is also the worldwide market leader in the field of optical aerosol spectrometers and filter testing systems.

Today, one would describe it as a start-up with which Leander Moelter began his exemplary career 35 years ago as an aerosol technology specialist in a residential building in Eggenstein-Leopoldshafen, Baden. In 1979, he had successfully completed his studies in precision engineering with a focus on communications engineering at the University of Applied Sciences of Karlsruhe, and he was already responsible for development and sales as a co-partner in a manufacturer of measuring equipment for laser Doppler anemometers. He was also a member of the VDI working group „Measurement of Particles“. However, the aerosol generation systems described in the VDI guidelines were mostly used as laboratory setups only, and the sole manufacturer of suitable measuring equipment was located in the U.S..

Although aerosol technology with fine dust measurement and air quality monitoring, things that are so self-evident today, was an area that was hardly noticed in Germany and Europe at that time, Leander Moelter recognized this as a market opportunity and discussed the plan to found a company to measure particles together with his brother Wolfgang and Fritz Munzinger. The resulting business concept convinced even the highest committees: Moelter emerged as the third winner out of more than 1,000 participants in the „Ways to self-employment“ competition organized by the Capital magazine.

September 12, 1983 was the birth of the now so successful Palas GmbH, which was to become the worldwide market leader in aerosol production, dilution and particle measurement technology in the years to come.

One of the success factors of the young Palas GmbH were the annual scientific platforms on the subject of aerosol technology, which had been established early on. Leander Moelter was also a member of the round table for the founding of Technologiefabrik Karlsruhe, which also included the then Prime Minister of the State of Baden-Wuerttemberg Lothar Spaeth, representatives of the Chamber of Industry and Commerce and the University of Karlsruhe. Just one year later, in the summer of 1984, Palas GmbH moved from the residential building to the newly founded Technologiefabrik, which, from the very beginning, was regarded as an „incubator“ for many later highly successful companies.

Palas® counts

Daily in the media today, but still uncharted territory at that time: Diesel soot emissions. For their accurate measurement and analysis, Palas GmbH developed, together with the renowned Fraunhofer Gesellschaft, a filter photometer, which was followed in 1985 by the first saleable filter media test stand. The system was rightly celebrated as an innovation at the Filtech international trade fair in Utrecht: It was the world’s first measuring technology to evaluate the efficiency of a filter depending on particle size.

As early as 1986, the young Palas GmbH with only three employees developed ten products, such as the RBG and BEG dust feeders. The AGF aerosol generators are used to nebulize liquids, and the VKL dilution systems are used to dilute highly concentrated aerosols.

The installation of a particle counter of Russian origin into a filter test system and the subsequent license agreement with Dr. Umhauer & Prof. Loeffler from the University of Karlsruhe for in-house production at Palas® under the product name Particle Counter Sizer PCS 2000 proved to be particularly visionary.

Smaller, lighter, more accurate

While the first system still weighed 28 kg and required a peripheral zone correction, this was not necessary with the T-iris and fiber optic technology developed as part of the C1 program funded by the State of Baden-Württemberg, which led to the construction of the 2.8 kg light welas® system, a white light aerosol spectrometer, in 2000.

Between 1990 and 2000, the increasingly higher measuring accuracy under extreme conditions such as overpressure, temperatures from -90° to 250°, as well as the higher miniaturization meant a breakthrough in aerosol technology. Today, the smallest device weighing only 200 grams is light as a feather, can be wirelessly controlled and is used in numerous industries.

A leap into digitalization

Entering the digital world, Palas® also revolutionized the aerosol technology when they implemented a digital platform for the welas® system in 2008. This allowed the particle signals to be better analyzed and measured in even higher concentrations.

„Count what is countable, measure what is measurable, and make measurable what is not measurable!“ In accordance with this principle of Galileo Galilei, the development of measurements of the smallest fine dust fractions in the micrometer range (PM10 and PM2.5) finally followed. With the introduction of the Fidas® fine dust measuring instruments (Finedust aerosol spectrometer) Leander Moelter quickly realized that this was the beginning of a completely different category of measuring instruments and global markets: Palas® now entered the new territory of the worldwide increasing environmental measuring technology with completely new target groups, which, however, required internationally recognized certifications and new dimensions of development, production and sales.

Motivation and Innovation Boost through Lean Management

In 2013, together with his new R&D director Dr.-Ing. Maximilian Weiß and a management consultancy, Leander Moelter decided to streamline processes, flatten hierarchies and perform certification compliant with the ISO 9001 quality management system. At the same time, the employees were more closely involved through short communication channels.

Despite the initial skepticism of the workforce towards the new lean management, the program proved to be a complete success: Identification with the company, motivation and inventiveness, resulting in innovations, especially in the development of new nanoparticle and fine dust measuring systems for environmental use, brought Palas® further ahead. The shareholders invested all profits exclusively in development. Expansion and increases in sales led to revenues of five million Euros in 2014, an increase of 26 percent from the previous year.

Today and tomorrow

Today, the Fidas® fine dust measuring systems – highly flexible stationary and mobile devices with the highest measuring accuracy that can also be applied in drones – are, at 50 per cent share, the mainstay of revenues amongst the roughly 150 products of Palas GmbH, which meanwhile grew to 68 employees.

The area of fine dust measurement offers considerable market opportunities in the future. Leander Moelter and Dr.-Ing. Maximilian Weiß, the other managing director of the company have since long recognized that air testing is not limited to outdoor applications only. Looking at the leading Asian countries in this field, interior monitoring in office buildings, schools and other buildings is becoming more and more important, and the demand for highly specialized equipment is increasing.

The subject of fine dust has also reached filter test stands in the meantime, with particle size distribution in the range of 0.3µm to 10µm being adapted even more closely to realistic conditions in future filter development, thus reacting to the real-world requirements of recent years. These new regulations are summarized in the ISO 16890 standard, which Palas® has already started to implement in the filter test benches and offers initial solutions.

A big success factor of Palas GmbH is its wide coverage of many customers and industries: In addition to federal and regional authorities, this includes the areas of automotive, environmental technology, health care and pharmacy, to which Palas GmbH supplies complete systems directly or via experienced local sales partners. In addition, Palas® supports its customers with know-how, seminars and trainings in all matters of aerosol technology and supplies everything from a One-Stop Shop. The company is thus well positioned equipped for the future as a global supplier of aerosol spectrometers and filter test systems.

Since 35 years, Palas GmbH is developing, producing and selling measuring instruments and filter test benches in the fields of aerosol technology and particle measurement. Today, Palas® is one of the international market leaders in numerous product fields. The headquarters are located in Karlsruhe, Baden-Wuerttemberg, and the measuring instruments are used worldwide – currently via a network of sales partners in approx. 50 countries worldwide.

Further information about Fidas® and other Palas® product lines can be found at www.palas.de

Company-Contact
Palas GmbH
Hannah Horn
Greschbachstraße 3b
76229 Karlsruhe
Phone: +49 (0)721 96213-0
E-Mail: hannah.horn@palas.de
Url: http://www.palas.de/

Press
Sylvia Lermann Public Relations
Sylvia Lermann
Enzianstr. 2c
85591 Vaterstetten
Phone: 08106-300 899
E-Mail: sylvia@lermann-pr.com
Url: http://www.lermann-pr.com

Science Research Technology

„Unmet Medical Need“ Retinitis pigmentosa: this challenge can only be solved together

RI Forum 2018: International retinal experts discuss retinal implants

"Unmet Medical Need" Retinitis pigmentosa: this challenge can only be solved together

International RI-Forum 2018 with retinal experts from all over Europe (Source: Retina Implant AG)

(Reutlingen / Vienna) – On the fringe of this year’s EURETINA congress that took place in Vienna from 20 to 23 September 2018, retinal experts from all over Europe met for the second international RI-Forum. More than 20 specialists followed the invitation of Retina Implant AG and discussed the topic:

Addressing the Unmet Medical Need of Retinitis pigmentosa (RP): teaming up to pave the way for today`s available methods

The medical challenge of treating the hereditary retinal disease RP is huge and in many cases it leads to blindness. A therapy that heals all forms of this disease is not in sight, despite great efforts and initial success with gene therapy approaches. „It continues to require the combined effort of science, medicine and industry to improve the situation for many RP patients,“ explained Dr. Alfred Stett, Chief Technology Officer of Retina Implant AG that hosted the expert panel. „Our electronic implant is already available to people who are blind from RP – regardless of the genetic cause of retinal disease.“

The Reutlingen-based Retina Implant AG has developed a retinal implant that can partially restore vision in people who have no or only bare light perception due to various forms of degenerative retinal diseases such as RP. Reimbursement is already available in Germany and France. „The subretinal implant is absolutely resilient in terms of function and safety. And it’s available,“ said Professor Florian Gekeler, Medical Director at the Katharinenhospital Stuttgart in Germany.

Professor Robert MacLaren, Professor of Ophthalmology at the University of Oxford UK, is convinced by the implant: „The electronic retinal implant has both light sensitivity and retinal stimulation built into it – hence when placed under the retina it truly replaces the role of photoreceptors, which are the light sensitive cells lost in patients who become blind from retinitis pigmentosa.“

The fact that there are still some challenges to overcome is accepted among all specialists in the group. „We observe that the visual perceptions generated by the implant are steadily improving with regular vision training. This has led us to develop a rehabilitation and training concept that allows patients to progressively train the use of the implant and certain visual abilities,“ explains Dr. Stett.

In addition to questions about rehabilitation, technology and surgery, the clinical experts also discussed in depth the selection of suitable patients. „Some of the most experienced international retinopathy experts have joined this RI-Forum because exchanges and collaboration need to be stepped-up to jointly overcome all barriers to existing therapies – from both patients‘ and physicians‘ perspectives,“ Prof. Gekeler summed up the evening.

About Retina Implant AG
Retina Implant AG researches and develops innovative treatments and high-tech products for people suffering from retinitis pigmentosa (RP). The subretinal RETINA IMPLANT Alpha AMS can help blind patients regain a certain degree of useful sight. The CE-approved microchip is implanted beneath the retina (subretinally) at specialist RI implantation centres.
Transcorneal electrical stimulation (TES treatment) with the RI OkuStim® system offers RP patients with sufficient residual vision the opportunity to slow down the progression of the disease.
The company, based in Reutlingen, employs around 45 people and is managed by Reinhard Rubow (CEO and speaker of the Management Board), Jürgen Klein (Member of the Board, Sales & Marketing) and Dr. Alfred Stett (CTO, Member of the Board).

Company-Contact
Retina Implant AG
Volker Hiller
Gerhard-Kindler-Str. 13
72770 Reutlingen
Phone: + 49 71 21 3 64 03 – 282
E-Mail: volker.hiller@retina-implant.de
Url: https://www.retina-implant.de/en/

Press
Zeeb Kommunikation GmbH
Anja Pätzold
Hohenheimer Straße 58a
70184 Stuttgart
Phone: 0711-60 70 719
E-Mail: info@zeeb.info
Url: http://www.zeeb-kommunikation.de

Science Research Technology

Innovative mass finishing process increases the efficiency of turbines

Specially selected grinding media improve the airflow characteristics of blades.

Innovative mass finishing process increases the efficiency of turbines

The MV multivibrators are equipped with high-speed imbalance motors.

At the ALUMINIUM 2018 exhibition Walther Trowal presents its new process for the gentle surface finishing of guide vanes used in turbines and compressors. It creates very smooth surface readings and, thus, optimizes the airflow through the guide vanes.

After they have been milled from a cast block of aluminium, guide vanes for turbines or compressors require a very smooth surface to insure optimum airflow around every single blade. To date this required a complex and costly mechanical process.

Walther Trowal has recently developed a method that allows the gentle smoothing of the guide vanes after milling without rounding the leading edges beyond the acceptable tolerances – an important factor for increasing the efficiency of jet engines.

Basis for the new process are the rotary multi vibrators of the model range MV allowing the processing of guide vanes with diameters of up to 800 mm. The company utilizes special, extremely small ceramic grinding media, which provide not only optimum surface coverage on the work pieces but also smoothens the surface at the root of the vanes.

The guide vanes, but also blisks, are mounted to a fixture that is magnetically attached to the base of the processing bowl. This ensures that the overlapping, high-frequency vibrations from the multi vibrator are transferred to the work piece, causing intensive contact between the media and the vane surface areas.

The result of the fully automatic finishing process: The milling lines from the preceding machining step have been ground out creating a very smooth surface. With the new process Walther Trowal reduces the Ra surface readings from 4.0 down to 1.0 µm with only minimal rounding of the leading edges. This innovative mass finishing process creates ideal conditions for an optimum airflow through the guide vanes.

At the ALUMINIUM 2018 Walther Trowal also presents rotary vibrators used for the surface finishing of aluminium castings including the removal of burrs.

Walther Trowal at ALUMINIUM 2018
Düsseldorf, September 18 – 22, 2018
Hall 12, Stand G50

Facts about Walther Trowal

For 85 years Walther Trowal has been a pioneer and market leader in various surface treatment technologies. The company offers modular and custom engineered solutions for a wide range of surface treatment problems.

Initially only making vibratory finishing equipment, over the years Walther Trowal has continuously broadened its product range and today offers a wide portfolio of equipment and services for improving all kinds of surfaces, e.g. mass finishing, part cleaning, shot blasting and drying of a wide spectrum of work pieces, last but not least, the coating of mass produced small parts.

Walther Trowal offers not only various types of equipment but complete surface treatment systems: By linking the various equipment modules and automating the complete process, we are able to precisely adapt our process technologies to the technical requirements of our customers. This also includes various types of peripheral equipment and process water cleaning and recycling systems. Of course, we also offer comprehensive pre- and after-sale service like sample processing in one of our demonstration labs and global repair and maintenance service.

Walther Trowal serves many customers in many industries around the world. For example, in the automotive and aerospace industry, medical engineering and wind power generation.

Company-Contact
Walther Trowal GmbH & Co.KG
Georg Harnau
Rheinische Str. 35-37
42781 Haan, Germany
Phone: +49 2129.571-0
Fax: +49 2129.571-225
E-Mail: info@walther-trowal.de
Url: http://www.walther-trowal.de

Press
VIP Kommunikation
Regina Reinhardt
Dennewartstraße 25-27
52068 Aachen, Germany
Phone: +49.241.89468-24
Fax: +49.241.89468-44
E-Mail: reinhardt@vip-kommunikation.de
Url: http://www.vip-kommunikation.de

Science Research Technology

GKN Powder Metallurgy Partners with HP and Volkswagen to Bring Metal 3D Printing to Mass Production

Partnership Set to Disrupt Traditional Manufacturing, Break Design Barriers and Accelerate the Adoption of Binder Jetting Technology

GKN Powder Metallurgy Partners with HP and Volkswagen to Bring Metal 3D Printing to Mass Production

Peter Oberparleiter, CEO GKN Powder Metallurgy

Chicago, IL – September 11, 2018 – GKN Powder Metallurgy, a leading innovation development partner of the manufacturing industry, today announced a strategic collaboration with HP Inc. at the 2018 International Manufacturing Technology Show (IMTS). The company will be the first to deploy the just-launched HP Metal Jet, a groundbreaking binder jetting technology, into its factories to produce functional metal parts for auto and industrial leaders, including Volkswagen and Wilo, and for companies around the world.
Together with HP, GKN Powder Metallurgy is working toward a vision of driving the global industrialization of additive manufacturing. The HP Metal Jet launch represents a paradigm shift in 3D printing for all markets as the new printer increases users‘ productivity up to 50 fold, compared to other 3D printing methods, at nearly half the cost of other binder jetting systems. The technology will enable GKN Powder Metallurgy to transform future product thinking and traditional manufacturing on behalf of its customers by reducing the time-to-market for mass-produced parts from months to weeks, lowering development costs, and providing greater design and manufacturing flexibility.

„Our vision for additive manufacturing in the enterprise moves beyond prototypes and small-series production and into mass production. We see a future where every modern digital company will have a cutting-edge 3D printer in their facilities, enabled by GKN technology, design and support, to produce metal parts in 24 hours. This strategic partnership with HP is the tipping point to accelerate that vision,“ said Peter Oberparleiter, CEO of GKN Powder Metallurgy. „Powder production and metal part processing are part of our DNA, and we have a long history of collaborating with customers and industrializing solutions that bring great benefits to the entire industry. As we join forces with HP, we want our customers to challenge us to break design barriers and accelerate the adoption of binder jetting technology as it is a wonderful compliment to our existing Additive Manufacturing technology offerings.“

As the world’s largest producer of metal parts, GKN Powder Metallurgy is uniquely positioned to advance the development of the binder jetting industry. By integrating the HP Metal Jet into the workflow across its plants worldwide, GKN Powder Metallurgy will leverage its metal expertise to engineer new powders based on customer needs and help them design parts they did not realize were possible. The company will build on its foundation of sintering 13 million metal parts per day and continue on the path to Industry 4.0, since binder jetting is a highly digital process and GKN Powder Metallurgy has already digitized its factory floors.

„HP is proud to partner with GKN Powder Metallurgy to bring the power of 3D mass production to the largest industries on earth, such as the auto and industrial sectors,“ said Stephen Nigro, President of 3D Printing, HP Inc. „The combination of HP’s breakthrough Metal Jet technology and GKN’s engineering and manufacturing leadership, promises to enable the production of millions of high-quality, low-cost 3D-printed final parts.“

In the first half of 2019, customers will be able to receive industrial-grade parts in higher quantities. GKN will produce parts using HP Metal Jet to ensure the highest standards of engineering and production quality. GKN Powder Metallurgy will be the only partner using the HP Metal Jet within the automotive and industrial market until the machine becomes generally available in 2020. For more information about this partnership, visit https://www.gkn.com/hp. To connect with GKN Powder Metallurgy at IMTS, join them at Booth #121602.

GKN Powder Metallurgy is your full metal shapes solutions provider, shaping powder metal into high performance and high precision components. We provide leading powder metal expertise and process experience to transform ideas into production. The company consists of GKN Hoeganaes, GKN Sinter Metals, and GKN Additive to provide powder materials, conventional components, and Additive Manufacturing production. We combine three focused businesses under one brand. Together we are over 7,400 problem solvers in over 34 locations, setting our global engineering network at the highest standard.

Contact
GKN Sinter Metals Engineering GmbH
Susanne Trautmann
Krebsöge 10
42477 Radevormwald
Phone: +49 (2289) 895980
E-Mail: Susanne.Trautmann@gkn.com
Url: https://www.gkn.com/hp

Science Research Technology

API Manufacturing – Future Growth Predictions – 2021

API Manufacturing - Future Growth Predictions - 2021

Browse 369 market data tables and 46 figures spread through 312 pages and in-depth TOC on „Active Pharmaceutical Ingredients/API Market“
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The global Active Pharmaceutical Ingredients market is expected to reach USD 213.97 Billion by 2021 from USD 157.95 Billion in 2016, growing at a CAGR of 6.3% from 2016 to 2021.

On the basis of type, the active pharmaceutical ingredients market is segmented into innovative and generic APIs. The innovative APIs segment is estimated to command the largest share in 2016.

Some of the major factors contributing to its large share include growing demand for innovative therapeutics for treatment of dreadful diseases, especially cancer, the increase in the number of FDA approvals for new molecular entities and the higher prices of innovative APIs (as compared to generics).

On the basis of type of manufacturer, the active pharmaceutical ingredients market is segmented into captive and merchant API manufacturers.

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The APIs market, on the basis of type of synthesis, is segmented into synthetic and biotech APIs. Synthetic APIs is estimated to dominate this market in 2016.The large share of this segment can be attributed to the emergence of new synthetic molecules in the market, increasing number of new product approvals, less complex manufacturing and approval processes as compared to biologics and technological advancements in the method of synthesis.

However, the biotech APIs market is expected to grow at a substantially higher rate during the forecast period owing to advances in biotechnology, growing demand for biopharmaceuticals due to their specificity in action, their similarity with the natural biological compounds, and significant growth in the demand for monoclonal antibodies.

Based on product, the biotech active pharmaceutical ingredients market is segmented into monoclonal antibodies, hormones, vaccines, cytokines, fusion proteins, therapeutic enzymes, and blood factors.

In 2015, the monoclonal antibodies segment account accounted for the largest share of the global biotech active pharmaceutical ingredients market. Growing incidence of cancer, increasing investments in R&D, technological advances in genetic sequencing and target gene selection, and increasing application of mAbs in oncology reduced side effects as compared to chemotherapy are some of the major factors responsible for the large share of monoclonal antibodies in this market.

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Based on geography, the global active pharmaceutical ingredients market is segmented into North America, Europe, Asia, and the Rest of the World (RoW). North America is expected to account for the largest share of the market by the end of 2016. This large share can be attributed to various factors including increasing incidence of chronic diseases, increasing focus of the government on the growing adoption of generic drugs, rising demand for biologics and specialty drugs, and technological advances in API manufacturing.

Prominent players in the active pharmaceutical ingredients market include Pfizer, Inc. (U.S.), Novartis International AG (Switzerland), Sanofi (France), Boehringer Ingelheim (Germany), Bristol-Myers Squibb (U.S.), Teva Pharmaceutical Industries Ltd. (Israel), Eli Lilly and Company (U.S.), GlaxoSmithKline plc (U.K.), Merck & Co., Inc. (U.S.) and AbbVie Inc. (U.S.).

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Our 850 fulltime analyst and SMEs at MarketsandMarkets™ are tracking global high growth markets following the „Growth Engagement Model – GEM“. The GEM aims at proactive collaboration with the clients to identify new opportunities, identify most important customers, write „Attack, avoid and defend“ strategies, identify sources of incremental revenues for both the company and its competitors. MarketsandMarkets™ now coming up with 1,500 MicroQuadrants (Positioning top players across leaders, emerging companies, innovators, strategic players) annually in high growth emerging segments. MarketsandMarkets™ is determined to benefit more than 10,000 companies this year for their revenue planning and help them take their innovations/disruptions early to the market by providing them research ahead of the curve.

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Science Research Technology

World“s largest scale alkaline water electrolysis system with power of 10 Megawatt from Asahi Kasei selected for Fukushima Hydrogen Research Center

Düsseldorf, August 14, 2018 – Asahi Kasei and its subsidiary Asahi Kasei Engineering Corp. have received an order from Toshiba Energy Systems & Solutions Corp. for an alkaline water electrolysis system of the world-leading scale of 10 MW in a single unit to be installed at the Fukushima Hydrogen Research Field in Namie, Futaba, Fukushima, Japan.

The development of a large-scale alkaline water electrolysis system featuring high energy efficiency and outstanding responsiveness with fluctuating output was achieved based on Asahi Kasei“s world-leading chlor-alkali electrolysis technology. The project is being supported by Japan“s New Energy and Industrial Technology Development Organization (NEDO).

Toshiba Energy Systems & Solutions was commissioned by NEDO to implement a „Hydrogen from Renewable Energy Project“ in Namie, as a technological development project.

Integrated with a large-scale solar power generation plant, the electrolysis system will form a core part of the Fukushima Hydrogen Research Field scheduled for test operation in the autumn of 2019 and start-up in the summer of 2020.

Asahi Kasei“s alkaline water electrolysis system is an example of „power-to-gas“ technology to convert renewable energy into clean hydrogen which is expected to be widely utilized in transportation and industrial applications as a substitute for fossil fuel. The market is expected to grow significantly with the shift to a low-carbon society.

Participation in this project accords with Asahi Kasei“s medium-term strategic objective of providing solutions to society in the area of clean environmental energy.

About Asahi Kasei
Asahi Kasei Corporation is a globally active diversified technology company with operations in the Material, Homes, and Health Care business. The Material division encompasses fibers & textiles, petrochemicals, performance polymers, performance materials, consumables, battery separators, and electronic devices. The Homes division provides housing and construction materials to the Japanese market. The Health Care division includes pharmaceuticals, medical devices, and acute critical care devices and systems. With approximately 34,000 employees around the world, the Asahi Kasei Group serves customers in more than 100 countries.

Asahi Kasei is „Creating for Tomorrow“ with all operations sharing a common mission of contributing to life and living for people around the world. For more information, visit

www.asahi-kasei.co.jp/asahi/en/
www.asahi-kasei.eu/

If you have any queries, please address them to:

Company contact Europe
Asahi Kasei Europe GmbH
Sebastian Schmidt
Am Seestern 4
40547 Düsseldorf
Phone: +49 (0)211 280 68 139
E-mail: Sebastian.Schmidt@asahi-kasei.eu

Press contact
financial relations GmbH
Henning Küll
Louisenstraße 97
61348 Bad Homburg
Telefon: +49 (0) 6172 27159 12
Phone: +49 (0) 175 903 42 29
E-Mail: h.kuell@financial-relations.de

The Asahi Kasei Group is a diversified group of companies led by Asahi Kasei Corp., with operations in the Material, Homes, and Health Care business sectors. Asahi Kasei distributes its innovative technologies and unique materials on markets worldwide.
With more than 30,000 employees around the world, the Asahi Kasei Group serves customers in more than 100 countries. Asahi Kasei is „Creating for Tomorrow“ with all operations sharing a common mission of contributing to life and living for people around the world.

Company-Contact
Asahi Kasei Europe GmbH
Sebastian Schmidt
Am Seestern 4
40547 Düsseldorf
Phone: +49 (0)211 280 68 139
E-Mail: Sebastian.Schmidt@asahi-kasei.eu
Url: https://www.asahi-kasei.eu/

Press
financial relations GmbH
Henning Küll
Louisenstraße 97
61348 Bad Homburg
Phone: +49 (0) 6172 27159 12
E-Mail: h.kuell@financial-relations.de
Url: http://www.financial-relations.de

Science Research Technology

Gentle finishing of extremely hard surfaces

Overlapping rotational work piece movement is the basis for even, all-around surface finishes

Gentle finishing of extremely hard surfaces

The spindles allow the processing of batches of up to 18 work pieces. For this photo different work

At this year“s IMTS Walther Trowal is introducing the new drag finisher M-TMD 6M for treating high-value components that require a first-class surface quality. The new drag machines will place a mirror polish on the hardest materials – even on ceramic components. With these machines the costs for polishing can be reduced to a fraction of the costs for manual surface grinding and polishing. But even more important: They ensure absolutely repeatable, high-quality finishing results within an extremely narrow tolerance band.

Walther Trowal developed these new machines specifically for treating high-value components requiring extremely careful handling for the complete finishing process. For example, they are utilized for finishing the surface of turbine blades, impellers for turbo chargers, precision components for pumps and compressors as well as for orthopedic implants.

The new drag machines of the M-series have a carousel with multiple rotating workstations. In turn each workstation is equipped with spindle heads containing several spindle drives onto which the work pieces are attached with special fixtures. In addition, these machines also contain a stationary work bowl filled with grinding or polishing media. As the work pieces are „dragged“ through the stationary media mass, the simultaneous rotational work piece movement by carousel, workstations and spindles creates different overlapping patterns, which ensure an even and intensive coverage of the complete work piece surface.

Christoph Cruse, director of sales at Walther Trowal, foresees a big demand for these machines at some of his customers who produce delicate, high-value components. He explains: „With our new machines we want to assist the manufacturers of work pieces that must receive the best possible surface finish, and where even the slightest surface flaw or scratch might cause them to be scrapped. Furthermore, we target parts where deviations from the dimensional specifications of a few thousands mm can be a detrimental. The M-TMD drag finishers with their perfect surface coverage open brand-new possibilities for finishing such work pieces.“

Die M-TMD 4 drag finisher is equipped with four work stations and can process 12 parts in one single batch; the M-TMD 6 – with six work stations allows batch sizes of up to 18 pieces.

At this year“s IMTS Walther Trowal also displays a range of mass finishing equipment including rotary vibrators, the MV multi vib vibrators and a high-energy centrifugal disk finishing machine.

One drag finishing success story:
Polishing of the extremely wear resistant ceramic coating on orthopedic implants

One example for the successful use of the new drag finishers is a process, specifically developed by Walther Trowal, for polishing of knee femorals made from a chromium-nickel alloy, which are covered with a ceramic coating applied with a special vapor deposit method. To date these parts had to be finished manually in time consuming multiple steps with the risk of high quality fluctuations.

After a pre-grinding step the ceramic coating is polished in the new M-TMD drag finisher with a polishing medium specifically developed for this application. The result: Although the ceramic coating is extremely hard, the drag finisher produces a very smooth, shiny and highly wear resistant finish from the initially rough surface condition. The new coating extends the fatigue life of the implants from to date about 20 up to 30 years!

In developing this process Walther Trowal took an entirely new approach. Instead of using relatively soft polishing materials the company is adding an extremely hard substance to the polishing medium, namely diamond powder.

Christoph Cruse explains the advantages of the new process as follows: „Soft materials can be polished relatively easily. But the manual polishing of extremely hard coatings has been extremely difficult, especially because an even surface finish is essential for the functionality of the component. In the case of vapor deposit coating, with a layer thickness of just a few microns, it is essential not to remove too much of the coating material from the part surface. With the M-TMD drag finishing technology and the new polishing media we have resolved this difficulty: The finish is absolutely even on the entire surface area of the implants.“

Walther Trowal at the IMTS 2018
September 10 – 15, 2018, Chicago, IL, USA
North Building, Level 3, Booth 236609

The technical details

In standard drag finishers the work pieces are directly mounted to the workstations and „dragged“ through the stationary media bed producing an extremely high processing intensity. This method is more than adequate for most work pieces and produces excellent finishing results.

The new M-TMD systems allow one additional rotational movement, namely that of the spindles mounted to the workstations. The multi-spindle heads on the workstations can be also be angled allowing the adaptation of the media coverage on the work piece surface to different work piece geometries.

All process steps, from cut-down, over surface smoothing to the final polishing, take place in the same machine, without having to remove the work pieces from the spindles.

The new drag finishers are suitable for dry as well as wet processing. In wet processes for cut-down, surface smoothing and, occasionally, for polishing, special finishing compounds are used. For the targeted edge radiusing within a tolerance range of a few thousands mm, like for example for tungsten carbide drill bits or milling tools, dry grinding media are utilized. Dry processing is also used for high gloss polishing with special pastes and polishing media.

Facts about Walther Trowal

For 85 years Walther Trowal has been a pioneer and market leader in various surface treatment technologies. The company offers modular and custom engineered solutions for a wide range of surface treatment problems.

Initially only making vibratory finishing equipment, over the years Walther Trowal has continuously broadened its product range and today offers a wide portfolio of equipment and services for improving all kinds of surfaces, e.g. mass finishing, part cleaning, shot blasting and drying of a wide spectrum of work pieces, last but not least, the coating of mass produced small parts.

Walther Trowal offers not only various types of equipment but complete surface treatment systems: By linking the various equipment modules and automating the complete process, we are able to precisely adapt our process technologies to the technical requirements of our customers. This also includes various types of peripheral equipment and process water cleaning and recycling systems. Of course, we also offer comprehensive pre- and after-sale service like sample processing in one of our demonstration labs and global repair and maintenance service.

Walther Trowal serves many customers in many industries around the world. For example, in the automotive and aerospace industry, medical engineering and wind power generation.

Walther Trowal in America

The recently opened „Tech & Training Centre“ of the Walther Trowal LLC in Grand Rapids, Michigan has, among other equipment, a test lab for the „Trowal Coating“ technology allowing interested customers informing themselves about the most suitable coating method for their work pieces.

Trowal has also extended its presence in Latin America by recently opening a sales office in Mexico, which is, of course, using the knowhow and resources of the Grand Rapids facility.

Company-Contact
Walther Trowal GmbH & Co.KG
Georg Harnau
Rheinische Str. 35-37
42781 Haan, Germany
Phone: +49 2129.571-0
Fax: +49 2129.571-225
E-Mail: info@walther-trowal.de
Url: http://www.walther-trowal.de

Press
VIP Kommunikation
Regina Reinhardt
Dennewartstraße 25-27
52068 Aachen, Germany
Phone: +49.241.89468-24
Fax: +49.241.89468-44
E-Mail: reinhardt@vip-kommunikation.de
Url: http://www.vip-kommunikation.de